The Efficacy of Sodium Lactate and Lactic Acid on Productive Performance, Immunity and Antioxidant State in Broiler Chickens

This study set out to examine the effects of two different dietary supplements, lactic acid or sodium lactate, on antioxidant status, productive performance, overall health, immune response, thyroid hormone levels, blood markers, immunity, and gut microbiota in growing broiler chickens up to 35 days old. An unmodified diet, one that included lactic acid, and one that included sodium lactate made comprised the three dietary treatments. A number of 180 Cobb 500 broiler chicks, sourced from a commercial hatchery, were split into three groups of sixty birds each for the meal tests. Each group had six replications. Throughout the three phases of development, recorded important performance indicators such as feed intake (FI), weight gain (WG) and feed conversion ratio (FCR). The blood samples were looked at for AST, creatinine, T3 and T4 thyroid hormones, and ALT. Among the blood antioxidants studied were malondialdehyde (MDA), total antioxidant capacity, and catalase. Hemagglutination inhibition (HI) titer against H5, H9, and Newcastle disease (ND) was a gauge of the immune response. E. coli and Lactobacillus species were counted as part of the gut microbiota study. While concurrently lowering MDA levels (P≤0.05), the findings showed that adding lactic acid and sodium lactate significantly improved BWG, FCR, and antioxidant status. An increase in HI titers is indicative of an improved immune response, which was achieved with both regimens. Sodium lactate or lactic acid raised total and Lactobacillus bacterial numbers in the intestines. Sodium lactate or lactic acid, when added to broiler feed, can improve performance, antioxidant status, immunity, and beneficial gut flora without negatively impacting health indices, making them a viable antibiotic option.