Mendelian randomization and single-cell analysis reveal causal relationships between renal clear cell carcinoma, kidney fibrosis, and inflammatory factors
Mendelian randomization analysis provides genetic evidence for causal relationships between kidney cancer and inflammatory factors, while excluding direct causal associations between kidney cancer and kidney fibrosis.
Authors
- Pei‐Hui Wang (ORCID: https://orcid.org/0000-0001-6853-2423)
- Haiping Jia
- Jiansong Shen (ORCID: https://orcid.org/0000-0002-3718-7986)
- Qianqian Li (ORCID: https://orcid.org/0000-0002-7508-2130)
- Xian Chen (ORCID: https://orcid.org/0000-0002-5234-5268)
- Tingting Ding (ORCID: https://orcid.org/0000-0003-2836-0086)
- Wentao Liu (ORCID: https://orcid.org/0009-0008-9257-8155)
Institutions
- Nantong University (CN)
- Yancheng First People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1007/s12672-025-03343-z
- Citations
- 1
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Government of Jiangsu Province