Isocitrate Dehydrogenase Wild-type Glioblastoma Resection Under Fluorescein Sodium and White Light Guidance Based on Response Assessment in Neuro-Oncology Resect Criteria: Fluorescein Significantly Enhances Complete Resection Rate of Enhanced Tumors

The CE tumor total resection rate guided by sodium fluorescein is superior to that of traditional WL surgery, offering the possibility of achieving a more thorough CE resection. Moreover, patients with methyltransferase gene methylation are more likely to achieve complete resection (CE) of the tumor without residual.

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Publication Details

Journal
Operative Neurosurgery
Published
2025-08-25
DOI
https://doi.org/10.1227/ons.0000000000001753
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Isocitrate Dehydrogenase Wild-type Glioblastoma Resection Under Fluorescein Sodium and White Light Guidance Based on Response Assessment in Neuro-Oncology Resect Criteria: Fluorescein Significantly Enhances Complete Resection Rate of Enhanced Tumors

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Isocitrate Dehydrogenase Wild-type Glioblastoma Resection Under Fluorescein Sodium and White Light Guidance Based on Response Assessment in Neuro-Oncology Resect Criteria: Fluorescein Significantly Enhances Complete Resection Rate of Enhanced Tumors

Xiangming Liu, Dabiao Zhou, Xuzhe Zhao, Rui Tao, Wancheng Li, Pei Yang, Yonggang Wang, Zhong Zhang, Yutao Zhang, Mi Shen, Jian He, Haibin Wan
article en

Abstract

The CE tumor total resection rate guided by sodium fluorescein is superior to that of traditional WL surgery, offering the possibility of achieving a more thorough CE resection. Moreover, patients with methyltransferase gene methylation are more likely to achieve complete resection (CE) of the tumor without residual.

Operative Neurosurgery
Capital Medical University (CN), Beijing Tian Tan Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 70%
Glioma Diagnosis and Treatment
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