Epstein-Barr virus-coded miR-BART19-3p promotes proliferation of EBV-associated gastric cancer by inhibiting GADD45B
Our study indicated Epstein-Barr Virus MicroRNA BART19-3p played an oncogenic role by a novel mechanism of inhibiting GADD45B in EBVaGC, which provides new insights and might be a potential therapeutic strategy for EBVaGC patients.
Authors
- Guangsheng Hu (ORCID: https://orcid.org/0000-0002-8293-0425)
- Jing Yang (ORCID: https://orcid.org/0009-0004-6493-5638)
- Zhifeng Liu (ORCID: https://orcid.org/0000-0001-5124-9824)
- Bin Zeng (ORCID: https://orcid.org/0000-0001-6847-5465)
- YueRu Han (ORCID: https://orcid.org/0000-0003-3280-3126)
- Robert Michael Go Gan (ORCID: https://orcid.org/0009-0007-2587-4379)
Institutions
- Hunan Cancer Hospital (CN)
- First Affiliated Hospital of University of South China (CN)
- University of South China (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s12967-025-06955-9
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Commission of Hunan Province
- Hunan Provincial Science and Technology Department
- Central South University
- Natural Science Foundation of Hunan Province
- Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study