T cells are associated with negative symptoms in persons with anti-gliadin antibody positive schizophrenia and related disorders
These hypothesis-generating findings suggest T cell dysfunction in AGA+ SRD, suggesting Tregs mitigating negative symptom severity, but also an unidentified other T cell population possibly contributing to negative symptomatology.
Authors
- Valerie Harrington (ORCID: https://orcid.org/0000-0001-7699-4089)
- Deepak Salem (ORCID: https://orcid.org/0000-0002-1060-8867)
- Daniel Roche (ORCID: https://orcid.org/0000-0001-6298-1519)
- Sarah M. Clark (ORCID: https://orcid.org/0000-0001-7328-0726)
- Deanna L. Kelly (ORCID: https://orcid.org/0000-0002-2176-518X)
- Zhenyao Ye
- Nevil J. Singh (ORCID: https://orcid.org/0000-0002-8384-9290)
- Robert W. Buchanan
- Monica V. Talor (ORCID: https://orcid.org/0000-0002-8275-5698)
- Shuo Chen (ORCID: https://orcid.org/0000-0002-0678-7380)
Institutions
- University of Maryland, Baltimore (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Schizophrenia Research
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1016/j.schres.2025.08.008
- Citations
- 2
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Institute of Mental Health