Myocardial dysfunction is linked to endothelial dysfunction in JIA patients: a study of novel aortic circumferential strain
There is currently an increasing body of evidence that cardiovascular disease partly results from low-grade inflammation, and there are also speculations that subtle myocardial dysfunction results from vascular involvement with impaired coronary relaxibility. We believe that this study adds more evidence to the latter. More studies involving more patients, notably at the molecular level, are needed to validate these results and to further understand their mechanisms.
Authors
- Antoine AbdelMassih (ORCID: https://orcid.org/0000-0001-8876-3229)
- Mohamad Samir AbdelWanis
- Rana Essam
- Eman Shafik Shafie (ORCID: https://orcid.org/0000-0002-5374-9723)
- Fatma El Zahraa Mostafa
- Mira M. Gales
Institutions
- Cairo University (EG)
- Shaikh Khalifa Medical City (AE)
- Cairo University hospitals (EG)
Publication Details
- Journal
- Pediatric Rheumatology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s12969-025-01073-8
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00