Myocardial dysfunction is linked to endothelial dysfunction in JIA patients: a study of novel aortic circumferential strain

There is currently an increasing body of evidence that cardiovascular disease partly results from low-grade inflammation, and there are also speculations that subtle myocardial dysfunction results from vascular involvement with impaired coronary relaxibility. We believe that this study adds more evidence to the latter. More studies involving more patients, notably at the molecular level, are needed to validate these results and to further understand their mechanisms.

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Publication Details

Journal
Pediatric Rheumatology
Published
2025-08-25
DOI
https://doi.org/10.1186/s12969-025-01073-8
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
Field-Weighted Citation Impact
0.00
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article

Myocardial dysfunction is linked to endothelial dysfunction in JIA patients: a study of novel aortic circumferential strain

Antoine AbdelMassih, Mohamad Samir AbdelWanis, Rana Essam, Eman Shafik Shafie et al.
Pediatric Rheumatology
Cardiovascular Function and Risk Factors
article

Myocardial dysfunction is linked to endothelial dysfunction in JIA patients: a study of novel aortic circumferential strain

Antoine AbdelMassih, Mohamad Samir AbdelWanis, Rana Essam, Eman Shafik Shafie, Fatma El Zahraa Mostafa, Mira M. Gales
article en

Abstract

There is currently an increasing body of evidence that cardiovascular disease partly results from low-grade inflammation, and there are also speculations that subtle myocardial dysfunction results from vascular involvement with impaired coronary relaxibility. We believe that this study adds more evidence to the latter. More studies involving more patients, notably at the molecular level, are needed to validate these results and to further understand their mechanisms.

Pediatric RheumatologyVol. 23(1)
Cairo University (EG), Shaikh Khalifa Medical City (AE), Cairo University hospitals (EG)
Openalex Percentile: Top 65%
Cardiovascular Function and Risk Factors
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