An innovative immunoassay for accurate aldosterone quantification: overcoming low-level inaccuracy and renal dysfunction-associated interference
This novel sCLIA method exhibited excellent analytical performance, combining the practical advantages of immunoassays with LC-MS/MS accuracy, thereby offering an ideal solution for large-scale primary aldosteronism screening in clinical practice.
Authors
- Xiaocui Shi (ORCID: https://orcid.org/0000-0002-7807-4478)
- Xiaojing Gao (ORCID: https://orcid.org/0000-0002-3094-1456)
- Hongying Cong
- Zhou Zhou (ORCID: https://orcid.org/0000-0002-7674-9857)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-0401-0519)
- Kaijuan Wang (ORCID: https://orcid.org/0000-0002-7105-8563)
- Zhangwei Gao
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1515/cclm-2025-0743
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00