Multiple cis-regulatory modules ensure robust tup/islet1 function in dorsal muscle identity specification
Our findings underscore the importance of CRM-mediated autoregulation and redundancy in ensuring robust and precise tup expression during muscle development. These results provide insights into how multiple CRMs coordinate gene regulation to ensure proper muscle identity and function.
Authors
- Aurore Pelletier (ORCID: https://orcid.org/0000-0002-7458-4964)
- Coralie Sengenès (ORCID: https://orcid.org/0000-0002-4820-6660)
- Jean‐Louis Frendo (ORCID: https://orcid.org/0000-0003-0118-5556)
- Alexandre Carayon (ORCID: https://orcid.org/0000-0003-4440-7112)
- Yannick Carrier
- Laurence Dubois
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Centre de Biologie du Développement (FR)
Publication Details
- Journal
- Skeletal Muscle
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s13395-025-00392-4
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Centre National de la Recherche Scientifique