Recurrence-free Survival as a Surrogate Endpoint for Overall Survival in Resectable Esophageal Cancer
This study demonstrated strong individual- and trial-level surrogacy between RFS and OS in resectable esophageal cancer across all perioperative treatments. These findings may accelerate perioperative treatment development by shortening follow-up in esophageal cancer trials.
Authors
- Thomas Ruhstaller (ORCID: https://orcid.org/0000-0002-4175-3784)
- Yuko Kitagawa (ORCID: https://orcid.org/0000-0001-6469-2155)
- Yasunori Sato (ORCID: https://orcid.org/0000-0002-7189-5126)
- Guillaume Piessen (ORCID: https://orcid.org/0000-0001-8243-8310)
- Bianca Mostert (ORCID: https://orcid.org/0000-0001-5193-0820)
- Kengo Nagashima (ORCID: https://orcid.org/0000-0003-4529-9045)
- Charlène J. van der Zijden (ORCID: https://orcid.org/0000-0002-3650-8303)
- Bas P. L. Wijnhoven (ORCID: https://orcid.org/0000-0003-4738-3697)
- Hiroya Takeuchi (ORCID: https://orcid.org/0000-0002-3947-0128)
- Shaoyuan Zhang (ORCID: https://orcid.org/0000-0002-6187-4313)
- Thomas Aparicio (ORCID: https://orcid.org/0000-0001-8834-6927)
- Jun Okui (ORCID: https://orcid.org/0000-0002-5226-1347)
- Fredrik Klevebro (ORCID: https://orcid.org/0000-0002-1695-4103)
- Satoru Matsuda (ORCID: https://orcid.org/0000-0001-8441-2755)
- Peter Thuss‐Patience (ORCID: https://orcid.org/0000-0002-8544-9872)
- Lijie Tan
- Hirofumi Kawakubo (ORCID: https://orcid.org/0000-0002-6246-7023)
- Takahiro Tsushima (ORCID: https://orcid.org/0000-0003-3551-7504)
- Magnus Nilsson
- Ken Kato
Institutions
- Centre National de la Recherche Scientifique (FR)
- Karolinska University Hospital (SE)
- Inserm (FR)
- Sun Yat-sen University (CN)
- University of Basel (CH)
- Keio University (JP)
- Université Paris Cité (FR)
- Université de Lille (FR)
- Fudan University (CN)
- Erasmus MC (NL)
- Karolinska Institutet (SE)
- Centre Hospitalier Universitaire de Lille (FR)
- Hamamatsu University School of Medicine (JP)
- Shizuoka Cancer Center (JP)
- Assistance Publique – Hôpitaux de Paris (FR)
- Keio University Hospital (JP)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Hôpital Saint-Louis (FR)
- National Cancer Center Hospital East (JP)
- Swiss Group For Clinical Cancer Research (CH)
- Erasmus MC Cancer Institute (NL)
- CANTHER - Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers (FR)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Annals of Surgery
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1097/sla.0000000000006919
- Citations
- 2
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.01