Does prophylactic antibiotic choice for total shoulder arthroplasty matter? A matched cohort analysis

Antibiotic prophylaxis choice for TSA may vary based on the surgeon's preference. Noncefazolin prophylaxis may not provide the same protection against PJI and overall infection as cefazolin prophylaxis. Cefazolin monotherapy is associated with lower infection rates compared to other noncefazolin regimens, suggesting that cefazolin should be used preferentially. However, prospective trials are required to further elucidate this finding.

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Publication Details

Journal
Journal of Shoulder and Elbow Surgery
Published
2025-08-25
DOI
https://doi.org/10.1016/j.jse.2025.07.017
Primary Topic
Antibiotic Use and Resistance
Type
article
Field-Weighted Citation Impact
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article

Does prophylactic antibiotic choice for total shoulder arthroplasty matter? A matched cohort analysis

Tej Joshi, Eitan M. Kohan, Frank G. Alberta, Daniel Calem et al.
Journal of Shoulder and Elbow Surgery
Antibiotic Use and Resistance
article

Does prophylactic antibiotic choice for total shoulder arthroplasty matter? A matched cohort analysis

Tej Joshi, Eitan M. Kohan, Frank G. Alberta, Daniel Calem, Akhil Katakam, Daniella Ogilvie
article en

Abstract

Antibiotic prophylaxis choice for TSA may vary based on the surgeon's preference. Noncefazolin prophylaxis may not provide the same protection against PJI and overall infection as cefazolin prophylaxis. Cefazolin monotherapy is associated with lower infection rates compared to other noncefazolin regimens, suggesting that cefazolin should be used preferentially. However, prospective trials are required to further elucidate this finding.

Journal of Shoulder and Elbow SurgeryVol. 35(3)
Rutgers, The State University of New Jersey (US), Hackensack University Medical Center (US)
Zero hunger
Openalex Percentile: Top 73%
Antibiotic Use and Resistance
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