Hospital-Wide Implementation, Clinical Outcomes, and Safety of Phenobarbital for Alcohol Withdrawal
In this quality improvement study, implementation of a weight-based phenobarbital order set for AWS in all care locations of a community hospital was associated with faster symptom resolution, shorter length of stay, and no differences in safety outcomes. These findings support the broader adoption of phenobarbital-based AWS treatment across diverse hospital settings.
Authors
- Benjamin J. Wolpaw
- Marion Granich
- Tessa L. Steel (ORCID: https://orcid.org/0000-0003-3159-5708)
- Nicholas J. Johnson (ORCID: https://orcid.org/0000-0001-9915-0591)
- Hannah Oren
- Ayushi Gupta (ORCID: https://orcid.org/0000-0002-4491-1258)
- Laura Quinnan-Hostein
- Katharine A. Bradley (ORCID: https://orcid.org/0000-0003-1933-4425)
- Kevin A. Hallgren (ORCID: https://orcid.org/0000-0001-8386-3984)
- H. Nina Kim
Institutions
- Kaiser Permanente Washington Health Research Institute (US)
- University of Washington (US)
- University of Washington Medical Center (US)
- Harborview Medical Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.28694
- Citations
- 5
- Primary Topic
- Alcoholism and Thiamine Deficiency
- Type
- article
- Field-Weighted Citation Impact
- 6.95