Congenital solitary neck ulcer as a presentation of Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is a neoplasm originating from immature haematopoietic myeloid precursor cells. It may uncommonly present with congenital ulcers. We report a case of a neonate admitted with a fever and a purulent congenital ulcer at the base of the neck, who, in the investigations, was diagnosed with LCH. This case highlights the importance of considering LCH in persistent, treatment-resistant cutaneous lesions in neonates and the necessity for biopsy and continuous monitoring.
Authors
- Azam Ghehsareh Ardestani
- Bahareh Abtahi‐Naeini (ORCID: https://orcid.org/0000-0003-1081-9477)
- Maryam Derakhshan (ORCID: https://orcid.org/0000-0003-0517-2111)
- Mahsa Pourmahdi‐Boroujeni (ORCID: https://orcid.org/0000-0003-4462-2883)
- Ali Emamjomeh (ORCID: https://orcid.org/0009-0002-7607-4041)
- Somayeh-Sadat Momenzadeh (ORCID: https://orcid.org/0009-0008-7800-7102)
Institutions
- Isfahan University of Medical Sciences (IR)
Publication Details
- Journal
- Skin Health and Disease
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1093/skinhd/vzaf050
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00