Multi-Omic Insight Into the Molecular Networks of Mitochondrial Dysfunction in the Pathogenesis of Schizophrenia
Our blood-based multi-omic analyses suggest ACADVL plays a role in schizophrenia pathophysiology. ACADVL represents a promising drug target for schizophrenia. Further validation and clinical trials are needed to explore ACADVL-based treatments for schizophrenia.
Authors
- Dabiao Zhou (ORCID: https://orcid.org/0000-0002-2683-2580)
- Ruiqi Jiang (ORCID: https://orcid.org/0000-0003-0440-1250)
- Zhigang Zhao (ORCID: https://orcid.org/0000-0003-3147-8544)
- Jiping Huo (ORCID: https://orcid.org/0000-0001-6611-966X)
- Shuxian Yang (ORCID: https://orcid.org/0000-0002-0918-2926)
- Kefu Yu
Institutions
- Beijing Tian Tan Hospital (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1093/schbul/sbaf145
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China