Measures of Brain Metabolism and Diffusion in Neonates of Mothers with Diabetes
The increase of myo-inositol in infants of mothers with diabetes may reflect a compensatory mechanism related to altered blood glucose to preserve and promote β-cell growth to enhance the production of insulin. The increase in mean diffusivity is consistent with decreased water diffusion, which potentially reflects abnormal changes in myelination and axonal loss.
Authors
- Kushal Kapse (ORCID: https://orcid.org/0000-0001-8363-5404)
- Nickie Andescavage (ORCID: https://orcid.org/0000-0002-6812-7898)
- Julius S. Ngwa (ORCID: https://orcid.org/0000-0002-6208-1331)
- Steve C. N. Hui (ORCID: https://orcid.org/0000-0002-1523-4040)
- Catherine Limperopoulos
- Nahla M.H. Elsaid
Institutions
- Children's National (US)
- George Washington University (US)
- Norwegian Womens Public Health Association (NO)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.3174/ajnr.a8982
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00