Severe hemolysis flare of refractory autoimmune hemolytic anemia with positive complement component C3d responsive to Iptacopan with cyclophosphamide and prednisone: a case report
Three refractory cases of AIHA showed good therapeutic efficacy after treatment with iptacopan combined with cyclophosphamide and prednisone. These cases provide a potentially effective treatment option for severe hemolytic episodes in refractory AIHA.
Authors
- Guangsheng He (ORCID: https://orcid.org/0000-0002-3944-5897)
- Yawen Zhang (ORCID: https://orcid.org/0000-0001-9613-4721)
- Yuemin Gong (ORCID: https://orcid.org/0009-0003-1873-6462)
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- Hematology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1080/16078454.2025.2548091
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province