Spectrum of Clinico-Epidemiological Profile of Scrub Typhus in a Tertiary Care Centre of North-East India

Introduction: Inspite of growing awareness scrub typhus remain a serious public health problem in Asia-Pacific area.It causes illness in one million people each year.In India, it is uncertain how widespread & burdensome scrub typhus is.It is difficult to differentiate from other acute febrile illness due to common symptomatology.Mizoram has a steep rise in scrub typhus & other rickettsial infection.Aizawl being worst affected with higher odds of deaths.Arunachal Pradesh also meet with many cases in previous years.Purpose of the study is to see wide spectrum of clinico-demographic profile of scrub typhus by using IgM ELISA.Material & Methods: A retrospective observational study was done in serology lab of TRIHMS, since January 2021 to December 2023.Total of 67 IgM ELISA confirmed cases were spotted.Their clinico-demographic profile were assessed and analysed statistically.Results: Among 604 suspected cases, 67 were scrub typhus positive.Proportion of positive cases in 2021, 2022, 2023 till August were 11.12%,10.43%,13%respectively.Male : Female ratio is 4:6.It is common (38.46%) in 21-30 years of age group.Clinically manifests as fever (55.38%) followed by headache (9.2%).Most patients belongs to Itanagar capital region (36.92%)& Papumpare (12.3%) district. Conclusion:Study showed an immense rise in scrub typhus.Adult (21-30yrs), males of Itanagar Capital Region (ICR) suffering from fever are at high risk.