Synthesis and Physicochemical Properties of Coumarin Derivatives as Antimicrobial Agents

A series of new cumarine Schiff base derivatives has been designed using in silico methods and synthesised as potential antimicrobial agents. Furthermore, the compounds were evaluated for their antibacterial and antifungal properties. In silico results indicate that all the compounds adhere to the Lipinski rule of five.

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Publication Details

Journal
International Journal of Basic Sciences and Applied Computing
Published
2025-08-25
DOI
https://doi.org/10.35940/ijbsac.l0537.11120825
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
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article

Synthesis and Physicochemical Properties of Coumarin Derivatives as Antimicrobial Agents

Manisha Pathania, Pravin K. Singh, Anita Singh
1 links
International Journal of Basic Sciences and Applied Computing
Synthesis and biological activity
article

Synthesis and Physicochemical Properties of Coumarin Derivatives as Antimicrobial Agents

Manisha Pathania, Pravin K. Singh, Anita Singh
article en

Abstract

A series of new cumarine Schiff base derivatives has been designed using in silico methods and synthesised as potential antimicrobial agents. Furthermore, the compounds were evaluated for their antibacterial and antifungal properties. In silico results indicate that all the compounds adhere to the Lipinski rule of five.

International Journal of Basic Sciences and Applied ComputingVol. 11(12)
Openalex Percentile: Top 84%
Synthesis and biological activity
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Synthesis and Physicochemical Properties of Coumarin Derivatives as Antimicrobial Agents — Manisha Pathania, Pravin K. Singh, et al. · International Journal of Basic Sciences and Applied Computing (2025) | TGRS Research Map | TGRS