A Chiroptical Switcher. Helical Inversion of Twisted Porphyrin Macrocycle Synergistically Controlled by Combined Stimuli of Solvent and Pressure
Herein, we report a chirally twisted porphyrin macrocycle, 1 is demonstrated to possess dynamically tunable chiroptical properties under hydrostatic pressure as an external stimulus. Upon hydrostatic pressurization, in halogenated solvents, the anisotropy (g) factor shifts from near zero to positive values, whereas in non-halogenated solvents, the g factor in-verts from negative to positive. These chiroptical switches are based on pressure-induced conformational change gov-erned by the interplay between macrocyclic flexibility and solvent polarity.
Authors
- Naoyuki Hisano (ORCID: https://orcid.org/0000-0002-1168-0385)
- Takeharu Haino (ORCID: https://orcid.org/0000-0002-0945-2893)
- Tomoyuki Hamachi
- Tomokazu Kinoshita
- Kouta Tanabe
- Gaku Fukuhara (ORCID: https://orcid.org/0000-0002-2189-8943)
Institutions
- Hiroshima University (JP)
- Kyushu University (JP)
- Shanghai Institute for Science of Science (CN)
- Institute of Science Tokyo (JP)
Publication Details
- Journal
- ChemRxiv
- Published
- 2025-08-25
- DOI
- https://doi.org/10.26434/chemrxiv-2025-v1nwk
- Primary Topic
- Photoreceptor and optogenetics research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tokyo Ohka Foundation for The Promotion of Science and Technology
- Japan Society for the Promotion of Science