Association of systemic immune-inflammation index with adverse outcomes in heart failure and preserved ejection fraction
In patients with HFpEF, higher SII values were positively associated with risk of death and HF hospitalization, with particularly strong prognostic value in diabetic patients. SII represents a promising, accessible biomarker for enhanced risk stratification in HFpEF.
Authors
- Fuad A. Abdu (ORCID: https://orcid.org/0000-0002-3222-4709)
- Abdul‐Quddus Mohammed (ORCID: https://orcid.org/0000-0003-0475-1760)
- Wenliang Che (ORCID: https://orcid.org/0000-0002-8840-5437)
- Yongqiang Luo (ORCID: https://orcid.org/0000-0003-4244-5297)
- Yawei Xu (ORCID: https://orcid.org/0000-0002-2175-6988)
- Guoqing Yin (ORCID: https://orcid.org/0000-0002-6628-7708)
- Redhwan M. Mareai (ORCID: https://orcid.org/0000-0002-5609-3352)
- Lu Liu (ORCID: https://orcid.org/0000-0002-4452-3079)
- Jiasuer Alifu (ORCID: https://orcid.org/0009-0006-5362-1056)
- Wen Zhang (ORCID: https://orcid.org/0000-0002-4690-2953)
- Yi-Chuan Chen (ORCID: https://orcid.org/0000-0001-6324-561X)
- Yang Su
Institutions
- Tongji University (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s12967-025-06964-8
- Citations
- 2
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Natural Science Foundation of Shanghai
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality