Implementation of Metformin Therapy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD): study protocol for a phase III, multi-centre, randomized, placebo-controlled trial evaluating the long-term efficacy of metformin in slo

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Publication Details

Journal
Trials
Published
2025-08-25
DOI
https://doi.org/10.1186/s13063-025-09010-6
Citations
1
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
1.82

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article

Implementation of Metformin Therapy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD): study protocol for a phase III, multi-centre, randomized, placebo-controlled trial evaluating the long-term efficacy of metformin in slo

Loreto Gesualdo, Andrew John Mallett, Gabor Mihala, Vivekanand Jha et al.
1 citations
Trials
Genetic and Kidney Cyst Diseases
1.82
article

Implementation of Metformin Therapy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD): study protocol for a phase III, multi-centre, randomized, placebo-controlled trial evaluating the long-term efficacy of metformin in slo

Loreto Gesualdo, Andrew John Mallett, Gabor Mihala, Vivekanand Jha, David Wayne Johnson, Andrea K. Viecelli, Paul J. Brent, Misa Matsuyama, Isabelle Kitty Stanley, Carmel M. Hawley, Charani Kiriwandeniya, Ragada El-Damanawi, Liza A. Vergara, Suetonia C. Green, Pushparaj Velayudham
article en
1 citations

Abstract

No abstract available for this paper.
TrialsVol. 26(1)
The University of Queensland (AU), Townsville Hospital (AU), Princess Alexandra Hospital (AU), Sheffield Kidney Institute (GB), George Institute for Global Health (IN), University of Bari Aldo Moro (IT), University of Otago (NZ), James Cook University (AU)
Tufts Medical Center, University of Otago, Australian Government, Postgraduate Institute of Medical Education and Research, Chandigarh, National Institute for Health and Care Research, Department of Health and Social Care, Indian Council of Medical Research, University of New South Wales, University of Sydney, University of Queensland, KU Leuven, Otsuka Pharmaceutical, Universität zu Köln, Universitätsklinikum Köln, Townsville Hospital and Health Service, Sheffield Teaching Hospitals NHS Foundation Trust, George Institute for Global Health, PKD Australia, Tufts University School of Medicine, University of Colorado Denver, Medical Research Council, National Health and Medical Research Council, Health Research Council of New Zealand, Efficacy and Mechanism Evaluation Programme, Faculty of Medicine and Health, University of Sydney
Openalex Percentile: Top 13%
Genetic and Kidney Cyst Diseases
1.82
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