The “Bone Block Technique”: Reconstruction of Bone Defects Caused by Osteomyelitis Using Corticocancellous Bone Blocks from the Iliac Crest and the Induced Membrane Technique

<b>Background:</b> The Induced Membrane Technique (IMT), commonly known as the Masquelet Technique (MT), has shown promising results in the reconstruction of bone defects caused by osteomyelitis. However, it is not a standardized surgical protocol but a treatment concept that has undergone various modifications, often yielding heterogeneous outcomes. <b>Methods:</b> This retrospective, single-center clinical cohort study included 49 patients treated with the Bone Block Technique (BBT) between 2013 and 2019 for bone defects resulting from osteomyelitis. The primary outcomes were time to bone healing, reinfection rate, and time to full weight-bearing. Additionally, infectious disease parameters, surgical site complications (SSCs), and epidemiological data were evaluated. <b>Results:</b> Data from 49 patients (mean age: 51 years, range: 17.6-76.9; 28.6% female) were analyzed, with a mean follow-up of 6.1 years (range: 4-10.5). The average bone defect length was 4.2 cm (range: 2.1-8.4 cm), predominantly involving the lower extremity. Primary bone consolidation was achieved in 93%, and secondary consolidation (requiring additional surgery) in 7%. Revision surgery due to recurrent infection was necessary in 16.6% of cases. The average time to full weight-bearing was 101.3 days. <b>Conclusions:</b> The BBT, as a modified approach based on the original IMT, represents a viable and reproducible option for bone defect reconstruction. When applied in accordance with the principles of the Diamond Concept, this technique facilitates reliable primary consolidation with a low complication rate.

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Journal
Life
Published
2025-08-25
DOI
https://doi.org/10.3390/life15091340
Primary Topic
Bone fractures and treatments
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article
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article

The “Bone Block Technique”: Reconstruction of Bone Defects Caused by Osteomyelitis Using Corticocancellous Bone Blocks from the Iliac Crest and the Induced Membrane Technique

Gunther O. Hofmann, Philipp Kobbe, Thomas Mendel, Friederike Klauke et al.
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Life
Bone fractures and treatments
article

The “Bone Block Technique”: Reconstruction of Bone Defects Caused by Osteomyelitis Using Corticocancellous Bone Blocks from the Iliac Crest and the Induced Membrane Technique

Gunther O. Hofmann, Philipp Kobbe, Thomas Mendel, Friederike Klauke, Steffen Langwald, Patrick Schröter, Marc Hückstädt, Christian Fischer, Sandra Schipper, Alexander Weissmann
article en

Abstract

<b>Background:</b> The Induced Membrane Technique (IMT), commonly known as the Masquelet Technique (MT), has shown promising results in the reconstruction of bone defects caused by osteomyelitis. However, it is not a standardized surgical protocol but a treatment concept that has undergone various modifications, often yielding heterogeneous outcomes. <b>Methods:</b> This retrospective, single-center clinical cohort study included 49 patients treated with the Bone Block Technique (BBT) between 2013 and 2019 for bone defects resulting from osteomyelitis. The primary outcomes were time to bone healing, reinfection rate, and time to full weight-bearing. Additionally, infectious disease parameters, surgical site complications (SSCs), and epidemiological data were evaluated. <b>Results:</b> Data from 49 patients (mean age: 51 years, range: 17.6-76.9; 28.6% female) were analyzed, with a mean follow-up of 6.1 years (range: 4-10.5). The average bone defect length was 4.2 cm (range: 2.1-8.4 cm), predominantly involving the lower extremity. Primary bone consolidation was achieved in 93%, and secondary consolidation (requiring additional surgery) in 7%. Revision surgery due to recurrent infection was necessary in 16.6% of cases. The average time to full weight-bearing was 101.3 days. <b>Conclusions:</b> The BBT, as a modified approach based on the original IMT, represents a viable and reproducible option for bone defect reconstruction. When applied in accordance with the principles of the Diamond Concept, this technique facilitates reliable primary consolidation with a low complication rate.

LifeVol. 15(9)
Jena University Hospital (DE), BG Klinikum Bergmannstrost Halle (DE), Martin Luther University Halle-Wittenberg (DE), Friedrich Schiller University Jena (DE)
Openalex Percentile: Top 70%
Bone fractures and treatments
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