Simultaneous quantitation of tigecycline, meropenem, polymyxin B in plasma, and protein-binding analysis in HSCT patients
Preliminary analysis suggests that BMI and serum albumin may influence PB1/PB2 binding in CRE-infected HSCT patients though larger cohorts are needed for confirmation. (clinical trial registration # 2021-0938-01).
Authors
- Junmiao Chen
- Wei Li (ORCID: https://orcid.org/0000-0002-1396-9692)
- Wei Shi (ORCID: https://orcid.org/0000-0002-6146-5894)
- Yan Gong (ORCID: https://orcid.org/0000-0003-4911-620X)
- Weijing Gong (ORCID: https://orcid.org/0000-0003-2114-7514)
- Zhuo Man
Institutions
- Union Hospital (HK)
- Beijing Health Vocational College (CN)
- Wuhan Union Hospital (CN)
- Beijing Radiation Center (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1080/17576180.2025.2546778
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China