Successful use of clozapine in a patient with schizophrenia comorbid with 22q11.2 deletion syndrome and multiple periventricular nodular heterotopia: A case report
Brain MRI and genetic testing-even when performed under sedation-may be valuable diagnostic tools in adolescents with treatment-resistant schizophrenia. Furthermore, the presence of structural brain abnormalities does not preclude the efficacy of clozapine, which may remain a viable and effective treatment option in such cases.
Authors
- Yasunori Oda (ORCID: https://orcid.org/0000-0002-4957-5847)
- Koichi Matsuyama
- Tsuyoshi Sasaki (ORCID: https://orcid.org/0000-0001-8502-6469)
- Tomihisa Niitsu (ORCID: https://orcid.org/0000-0003-2713-700X)
- Keisuke Hoshi
- Shintaro Shibata (ORCID: https://orcid.org/0009-0004-7057-7099)
- Fumiaki Yamasaki
- Fumiaki Yano (ORCID: https://orcid.org/0009-0000-4898-3905)
- Yusuke Nakata (ORCID: https://orcid.org/0009-0003-2816-3733)
- Kazuki Okada
- Takeru Saito
- Teruomi Iyo
Institutions
- Chiba University (JP)
- Chiba University Hospital (JP)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences Reports
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1002/pcn5.70195
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chiba University