Figure 1 from Patterns of HER2 Expression in Metastatic Prostate and Urothelial Cancers: Implications for HER2-Targeted Therapies

<p><b>A</b> and <b>B,</b> Representative micrographs of HER2 IHC staining in prostate cancer (<b>A</b>) and urothelial cancer (<b>B</b>) autopsy specimens. <b>C,</b> Number of patients with at least one tumor with the indicated HER2 IHC score, color coded by cancer type. <b>D,</b> Number of tumors across all patients with the indicated HER2 IHC score, color coded by cancer type. <b>E</b> and <b>F,</b> Percent of tumors expressing the indicated level of HER2 staining by IHC according to the tumor site sampled in prostate (<b>E</b>) and urothelial (<b>F</b>) cancer cohorts. Anatomic sites with only one representative tumor were excluded. PC, prostate cancer; UC, urothelial carcinoma.</p>

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Publication Details

Published
2025-08-25
DOI
https://doi.org/10.1158/2767-9764.29978438
Primary Topic
Prostate Cancer Treatment and Research
Type
article
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article

Figure 1 from Patterns of HER2 Expression in Metastatic Prostate and Urothelial Cancers: Implications for HER2-Targeted Therapies

Andrew Caleb Hsieh, Maria Tretiakova, Jessica E. Hawley, Colm M. Morrissey et al.
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Prostate Cancer Treatment and Research
article

Figure 1 from Patterns of HER2 Expression in Metastatic Prostate and Urothelial Cancers: Implications for HER2-Targeted Therapies

Andrew Caleb Hsieh, Maria Tretiakova, Jessica E. Hawley, Colm M. Morrissey, Michael Thomas Schweizer, Hung‐Ming Lam, Radhika A. Patel, Farinaz Shokri, Erolcan Sayar, Samantha L. Schuster, Petros D. Grivas, Meagan Chambers, Lawrence D. True, Gavin Ha, Roman Gulati, Heather H. Cheng, Bruce Montgomery, Funda Vakar‐Lopez, Michael C. Haffner, Peter S. Nelson, Ruben Raychaudhuri, Ilsa M. Coleman, Jonathan Lawrence Wright, Evan Y. Yu, Pushpa Itagi, Sonali Arora, Mohamed Adil, Thomas Persse, Hyun Jung Lee, Helen Richards
article en

Abstract

<p><b>A</b> and <b>B,</b> Representative micrographs of HER2 IHC staining in prostate cancer (<b>A</b>) and urothelial cancer (<b>B</b>) autopsy specimens. <b>C,</b> Number of patients with at least one tumor with the indicated HER2 IHC score, color coded by cancer type. <b>D,</b> Number of tumors across all patients with the indicated HER2 IHC score, color coded by cancer type. <b>E</b> and <b>F,</b> Percent of tumors expressing the indicated level of HER2 staining by IHC according to the tumor site sampled in prostate (<b>E</b>) and urothelial (<b>F</b>) cancer cohorts. Anatomic sites with only one representative tumor were excluded. PC, prostate cancer; UC, urothelial carcinoma.</p>

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Prostate Cancer Treatment and Research
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