Rare hepatic metastasis in classical adenoid cystic carcinoma of the breast: A case report

Adenoid cystic carcinoma of the breast (ACCB) is a rare and distinct form of triple-negative breast cancer, accounting for only 0.06-0.1% of all breast cancers. ACCB is characterized by a favorable prognosis and can be divided into three subtypes: Classical, solid and high-grade transformation. The classical type is the most common and has the least aggressive biological behavior, with rare occurrences of metastasis. By contrast, patients with the solid and high-grade transformation types are more likely to experience local recurrence and distant metastasis. The present report describes a rare case of hepatic metastasis in classical ACCB, and discusses its treatment and follow-up. Additionally, the current advancements in the management of ACCB are reviewed to provide insights for further understanding and clinical guidance.

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Publication Details

Journal
Oncology Letters
Published
2025-08-25
DOI
https://doi.org/10.3892/ol.2025.15241
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Rare hepatic metastasis in classical adenoid cystic carcinoma of the breast: A case report

Miduo Tan, Yangjing Ou, Taoli Wang, Wei Zhou et al.
Oncology Letters
Salivary Gland Tumors Diagnosis and Treatment
article

Rare hepatic metastasis in classical adenoid cystic carcinoma of the breast: A case report

Miduo Tan, Yangjing Ou, Taoli Wang, Wei Zhou, Lin Tang, Xiaohui Huang
article en

Abstract

Adenoid cystic carcinoma of the breast (ACCB) is a rare and distinct form of triple-negative breast cancer, accounting for only 0.06-0.1% of all breast cancers. ACCB is characterized by a favorable prognosis and can be divided into three subtypes: Classical, solid and high-grade transformation. The classical type is the most common and has the least aggressive biological behavior, with rare occurrences of metastasis. By contrast, patients with the solid and high-grade transformation types are more likely to experience local recurrence and distant metastasis. The present report describes a rare case of hepatic metastasis in classical ACCB, and discusses its treatment and follow-up. Additionally, the current advancements in the management of ACCB are reviewed to provide insights for further understanding and clinical guidance.

Oncology LettersVol. 30(5)
Central South University (CN), Zhuzhou Central Hospital (CN)
Openalex Percentile: Top 64%
Salivary Gland Tumors Diagnosis and Treatment
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