Yuye Jinhua Qingre Tablets Attenuate Acute Pharyngitis by inhibiting the Complement Cascade and C5a/C5aR1 Axis
Research indicates that YYJH exerts anti-inflammatory effects by regulating the classical complement pathway and the C5a/C5aR1 axis, inhibiting the production of inflammatory mediators and the activation of immune cells. This provides a theoretical basis for the molecular mechanisms underlying traditional Chinese medicine in the treatment of acute pharyngitis.
Authors
- Xiaoyu Tao (ORCID: https://orcid.org/0009-0000-0634-6254)
- Fanqin Zhang
- Leiming You (ORCID: https://orcid.org/0000-0002-8120-8916)
- Jiarui Wu (ORCID: https://orcid.org/0000-0002-1617-6110)
- Hua Luo
- Haojia Wang (ORCID: https://orcid.org/0000-0002-1457-8458)
- Yong Liang Guan (ORCID: https://orcid.org/0000-0002-9757-630X)
- Yifei Gao
- Siyu Guo (ORCID: https://orcid.org/0000-0002-3409-0185)
- Jiying Zhou (ORCID: https://orcid.org/0000-0003-1063-4181)
- Chao Wu (ORCID: https://orcid.org/0000-0002-6565-1707)
- Zhengsen Jin
Institutions
- Guangxi Medical University (CN)
- Beijing University of Chinese Medicine (CN)
- Hua Medicine (China) (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s13020-025-01191-1
- Primary Topic
- Andrographolide Research and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00