EXPLORING THE LINK BETWEEN THE 2D:4D RATIO, BLOOD PRESSURE, AND LIPID PROFILE IN A MALE POPULATION FROM NORTH INDIA.

Background: The 2D:4D finger length ratio, known for its sexual dimorphism and association with various traits, has been investigated as a potential marker for cardiovascular disease. This study aimed to determine if 2D:4D ratios correlate with coronary artery disease (CAD) in males, as assessed by ECG, 2D-ECHO, and coronary angiography. Methods: This cross-sectional study included 100 male subjects aged 30-80 years, divided into two groups: 50 with diagnosed CAD and 50 without. Digital calipers were used to measure the lengths of the index (2D) and ring (4D) fingers of both hands, with measurements taken twice for accuracy. Data were analyzed using appropriate statistical methods. Results: Males with CAD exhibited significantly higher 2D:4D ratios compared to those without CAD (P < 0.01). This finding indicates a positive correlation between elevated 2D:4D ratios and the presence of CAD in male subjects. Conclusion: This study suggests that the 2D:4D finger length ratio may serve as a potential marker for predisposition to CAD in males. Higher 2D:4D ratios were associated with a significantly increased likelihood of CAD, as confirmed by clinical assessments.