A retrospective study for the diagnostic value of chromosomal microarray analysis in fetuses with high-risk prenatal indications
CMA has a greater diagnostic value for screening chromosomal abnormalities, especially in pregnant women with normal karyotypes. The diagnostic yields of CMA for pregnancies with different indications greatly varied. CMA could serve as a first-tier test for structural anomalies, especially multiple anomalies, hydrops fetalis, cystic hygroma, and thickened nuchal translucency or nuchal fold.
Authors
- Junfang Xiao (ORCID: https://orcid.org/0009-0003-9136-7130)
- Bicheng Yang (ORCID: https://orcid.org/0000-0002-0137-6830)
- Hui Xiao (ORCID: https://orcid.org/0000-0002-1465-4596)
- Qing Lu (ORCID: https://orcid.org/0000-0001-6287-553X)
- Huizhen Yuan
- Huan Zhang (ORCID: https://orcid.org/0000-0002-2289-7707)
- Yanqiu Liu (ORCID: https://orcid.org/0000-0002-6123-5618)
- Yongyi Zou (ORCID: https://orcid.org/0000-0001-5869-7988)
- S. Huang (ORCID: https://orcid.org/0000-0002-1177-6758)
Institutions
- Jiangxi Maternal and Child Health Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-08-25
- DOI
- https://doi.org/10.3389/fgene.2025.1649253
- Citations
- 1
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.49