Case Report: Effective methotrexate removal by combined hemodialysis and polymeric resin hemoadsorption
This case demonstrates the effectiveness of combined HFHD and HA230 hemoadsorption as a bridging or alternative strategy when glucarpidase is delayed or unavailable. While evidence remains limited, it supports further investigation into extracorporeal MTX removal and contributes to the evolving field of Onconephrology.
Authors
- José Maximino Costa (ORCID: https://orcid.org/0000-0002-0408-7057)
- Isabel Oliveira (ORCID: https://orcid.org/0000-0002-0068-0806)
- José Mariz (ORCID: https://orcid.org/0000-0003-0240-4749)
- Marlene Alves Días (ORCID: https://orcid.org/0000-0001-9168-9066)
- Sérgio Chacim (ORCID: https://orcid.org/0000-0002-6316-8789)
- Hugo Ferreira (ORCID: https://orcid.org/0000-0002-1399-1953)
- Carla Nicolau (ORCID: https://orcid.org/0009-0002-8496-0377)
- Gonçalo de Câmara Negalha
Institutions
- IPO Porto (PT)
- Hospital Curry Cabral (PT)
- Hospital Garcia de Orta (PT)
Publication Details
- Journal
- Frontiers in Nephrology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.3389/fneph.2025.1644079
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto Português de Oncologia do Porto