Low-grade endometrial stromal sarcoma: a case report and literature review

By reviewing the patient's medical history, we gained new insights into the etiology, risk factors, and imaging characteristics of LG-ESS. Endometriotic lesions may serve as a source of LG-ESS. The use of morcellators and UAE in the treatment of benign uterine conditions can increase the risk of malignant tumors. Distinguishing LG-ESS on imaging can be challenging, but magnetic resonance imaging shows some suggestive features, including isointense or slightly hypointense signals on T1-weighted imaging, a mixed signal on T2-weighted imaging or a homogeneous high signal with internal hypointense bands, a high signal on diffusion-weighted imaging, and low apparent diffusion coefficient values, which may aid in differentiation.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-08-25
DOI
https://doi.org/10.3389/fonc.2025.1652010
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Low-grade endometrial stromal sarcoma: a case report and literature review

Chuqiao Chen, Xiaojing Zhao, Tingting Xie, Liang Wang
Frontiers in Oncology
Uterine Myomas and Treatments
article

Low-grade endometrial stromal sarcoma: a case report and literature review

Chuqiao Chen, Xiaojing Zhao, Tingting Xie, Liang Wang
article en

Abstract

By reviewing the patient's medical history, we gained new insights into the etiology, risk factors, and imaging characteristics of LG-ESS. Endometriotic lesions may serve as a source of LG-ESS. The use of morcellators and UAE in the treatment of benign uterine conditions can increase the risk of malignant tumors. Distinguishing LG-ESS on imaging can be challenging, but magnetic resonance imaging shows some suggestive features, including isointense or slightly hypointense signals on T1-weighted imaging, a mixed signal on T2-weighted imaging or a homogeneous high signal with internal hypointense bands, a high signal on diffusion-weighted imaging, and low apparent diffusion coefficient values, which may aid in differentiation.

Frontiers in OncologyVol. 15
Zhejiang Shuren University (CN), Second Affiliated Hospital of Zhejiang University (CN)
Zhejiang Traditional Chinese Medicine Administration
Openalex Percentile: Top 73%
Uterine Myomas and Treatments
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Low-grade endometrial stromal sarcoma: a case report and literature review — Chuqiao Chen, Xiaojing Zhao, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS