Comparative analysis of sex-dependent serum metabolomic patterns across the lifespan of rhesus macaques
These results highlight pronounced sex differences in metabolomic aging trajectories in rhesus macaques, particularly in lipid and amino acid metabolism. These findings underscore the importance of incorporating sex as a biological variable in aging studies and support the utility of rhesus macaques for identifying conserved, sex-specific biomarkers of biological aging.
Authors
- R. W. Goy (ORCID: https://orcid.org/0000-0003-3636-9515)
- Marina E. Emborg
- Amita Kapoor (ORCID: https://orcid.org/0000-0001-9708-6979)
- Jeanette M. Metzger
- Ludwig A. P. Metzler
Institutions
- University of Wisconsin–Madison (US)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-08-25
- DOI
- https://doi.org/10.3389/fgene.2025.1655325
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Rainwater Charitable Foundation
- National Institutes of Health