VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

<i>VCAM-1</i> is a novel prognostic biomarker driving immunosuppressive microenvironmental remodeling in GC. Furthermore, its dual roles in immune regulation highlight its potential to optimize GC immunotherapy.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-08-25
DOI
https://doi.org/10.3389/fgene.2025.1602929
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

Chuanfa Fang, Y. Liu, Chuanyuan Liu, Cheng Wu
Frontiers in Genetics
Cancer Immunotherapy and Biomarkers
article

VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

Chuanfa Fang, Y. Liu, Chuanyuan Liu, Cheng Wu
article en

Abstract

<i>VCAM-1</i> is a novel prognostic biomarker driving immunosuppressive microenvironmental remodeling in GC. Furthermore, its dual roles in immune regulation highlight its potential to optimize GC immunotherapy.

Frontiers in GeneticsVol. 16
Nanchang University (CN), Ganzhou People's Hospital (CN), Nanfang Hospital (CN), Southern Medical University (CN)
Health Commission of Jiangxi Province
Openalex Percentile: Top 69%
Cancer Immunotherapy and Biomarkers
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