Arctigenin Prevents Metabolic Dysfunction-associated Steatohepatitis by Inhibiting NLRP3/GSDMD-N Axis in Macrophages

ATG may inhibit the inflammatory cascade primarily by targeting macrophage NLRP3 inflammasomes, thereby preventing the progression of MASH.

Authors

Qin Pan (ORCID: https://orcid.org/0000-0001-5855-4952)
Tianyi Ren (ORCID: https://orcid.org/0000-0002-0844-7072)
Rui Xue (ORCID: https://orcid.org/0000-0002-1764-2072)
Qianren Zhang (ORCID: https://orcid.org/0000-0002-7202-9625)
Lu Jiang (ORCID: https://orcid.org/0000-0001-7283-1303)
Qiuhong Wang (ORCID: https://orcid.org/0009-0006-3789-445X)
Jian‐Gao Fan (ORCID: https://orcid.org/0000-0002-8618-6402)
Rui-Xu Yang