Efficacy Of Hyaluronic Acid Spray in Reducing Postoperative Pain, Swelling and Enhancing Soft Tissue Healing After Transalveolar Extraction of Endodontically Treated Mandibular Molars: A Comparative Study

Introduction: Transalveolar extraction of mandibular molars is a one of the common oral surgical procedure often associated with postoperative concerns such as pain, swelling, and delayed wound healing. To ensure the best possible patient comfort and recuperation, these issues must be effectively managed. A naturally occurring glycosaminoglycan, hyaluronic acid (HA) has drawn interest in oral and maxillofacial surgery because of its biocompatibility anti-inflammatory qualities, and tissue regeneration potential. Aim and Objectives: The aim of this study is to study efficacy of hyaluronic acid spray after transalveolar extraction of endodontically treated mandibular molars in reducing postoperative complications like pain and swelling and inducing early soft tissue healing. Materials And Methods: The study involves 60 individuals requiring transalveolar mandibular molar extractions, selection based on inclusion and exclusion criteria. Adhering to Helsinki Ethical Principles, patients were informed about the procedure, study goals, benefits, and risks. Written informed consent will be obtained. Complete case history was taken, and a treatment plan developed after evaluation and diagnosis. Patients are divided into two groups. In this study, patients divided into study group (n=30: HA sprayed) and control group (n=30: HA not sprayed). Patients were selected randomly for both groups. The clinical postoperative parameters like pain was measured using VAS scale, swelling was measured using tape measure method described by Gabka and Matsumara and soft tissue healing index was evaluated by Landry R, Turnbull R and Howley T soft tissue healing index on 1s ,3rd and 7th postoperative days. Results: There was significant difference between the groups in reducing postoperative pain, facial swelling and soft tissue healing. (P ≤0.05). Conclusion: Hyaluronic acid spray is useful for promoting early soft tissue healing and minimizing postoperative concerns related to pain and swelling following transalveolar extraction of Endodontically treated mandibular molars.