Diagnostic biomarkers for late-onset sepsis in pediatric intensive care: a retrospective cohort study
The combination of CRP, Lac, and IL-1β serves as a robust set of biomarkers for the differential diagnosis of LOS in pediatric ICU settings. Furthermore, PCT also serves as a critical biomarker for differentiating between Gram-negative and Gram-positive bacterial causes, aiding in more targeted clinical management.
Authors
- Ying‐Chun Shen (ORCID: https://orcid.org/0000-0001-8426-9071)
- Gang Li (ORCID: https://orcid.org/0000-0003-0422-1516)
Institutions
- Northwest Women's and Children's Hospital (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s12887-025-06017-5
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00