Genomic evidence links human dengue cases with undetermined serotypes to sylvatic lineages
This study provides the first genomic evidence of a recent sylvatic DENV2 spillover into humans in Malaysia, likely undetected by standard diagnostics due to genetic divergence. These findings underscore the urgent need to enhance surveillance tools and explore the sylvatic transmission cycle's role in dengue epidemiology.
Authors
- Mohd Rahim Sulong (ORCID: https://orcid.org/0009-0004-2255-2268)
- Zailiza Suli (ORCID: https://orcid.org/0000-0003-2036-9318)
- Rozainanee Mohd Zain (ORCID: https://orcid.org/0000-0002-5756-7660)
- Jeyanthi Suppiah (ORCID: https://orcid.org/0000-0002-4788-2149)
- Ming Keong Wan
- Murni Maya Sari Zulkifli
- Amir Hussin Adiee
- Nuraisyah Ramli
- Nur Ain Zahidah Zainudin
- Mazrul Effendy Dukut Soeharto
Institutions
- Ministry of Health (MY)
Publication Details
- Journal
- Tropical Medicine and Health
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s41182-025-00795-5
- Citations
- 1
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 1.88