Longitudinal changes in [18F]FDG PET brain metabolism as a prognostic marker in autoimmune encephalitis
Longitudinal [<sup>18</sup>F]FDG PET reveals distinct regional metabolic changes paralleling clinical recovery post-treatment in AE. Temporo-parietal metabolism correlates with relapses, clinical severity, and functional impairment, highlighting [<sup>18</sup>F]FDG PET as a biological tracker of disease activity throughout AE and its prognostic value.
Authors
- Stefano Raffa
- Luca Roccatagliata (ORCID: https://orcid.org/0000-0001-8029-3947)
- Luana Benedetti (ORCID: https://orcid.org/0000-0002-9540-9727)
- Giovanna Benvenuto (ORCID: https://orcid.org/0000-0001-7155-2935)
- Antonio Uccelli (ORCID: https://orcid.org/0000-0002-2008-6038)
- Giampaola Pesce (ORCID: https://orcid.org/0000-0002-6294-9110)
- Pietro Mattioli (ORCID: https://orcid.org/0000-0003-2563-5830)
- Flavio Villani (ORCID: https://orcid.org/0000-0002-2762-4599)
- Giacomo Bavestrello
- Federico Massa (ORCID: https://orcid.org/0000-0001-5667-204X)
- Emanuela Maria Mobilia (ORCID: https://orcid.org/0000-0003-2968-4154)
- Matteo Pardini (ORCID: https://orcid.org/0000-0002-4740-1982)
- Giacomo Rebella (ORCID: https://orcid.org/0000-0001-8625-1596)
- Anastasia Lechiara (ORCID: https://orcid.org/0000-0002-7839-640X)
- Dario Arnaldi (ORCID: https://orcid.org/0000-0001-6823-6069)
- Silvia Morbelli (ORCID: https://orcid.org/0000-0002-7833-6095)
- Denise Cerne (ORCID: https://orcid.org/0009-0003-5411-1187)
Institutions
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Ospedale Policlinico San Martino (IT)
- University of Turin (IT)
- University of Genoa (IT)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1007/s00259-025-07526-2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Genova