Evaluation of Antioxident and Antifungal Activity of Caesalpinia Bonducella Root Extract

Medicinal plants are a vital source of medications globally, offering low-cost treatments for various ailments. The seeds of Caesalpinia bonducella have been traditionally utilized to treat conditions such as leprosy, fever, edema, colic, malaria, and stomach pain. This study aimed to investigate the polar phytoconstituents and assess the antioxidant and antifungal activities of Caesalpinia bonducella root extract using solvent ethanol through the Soxhlet extraction method, potentially providing a natural alternative to synthetic antibiotics. Root of Caesalpinia bonducella was collected, authenticated, dried, and extract with ethanol, followed by evaluating the antioxidant properties using a DPPH assay method, the extract was mixed with DPPH solution and incubated in darkness. Absorbance was measured at 520 nm, with ascorbic acid as the standard for comparison. Antifungal activity against Aspergillus niger, Aspergillus flavus, and Candida albicans was assessed using microbiological assays. The ethanolic extract showed antioxidant scavenging activity of 87.83 µg/ml compared to ascorbic acid's 93.55 µg/ml. The extract was rich in secondary metabolites, including flavonoids, phenolic compounds, and alkaloids, which contributed to its antioxidant activity by effectively reducing DPPH radicals. The antifungal tests indicated notable efficacy against the tested fungi, the Caesalpinia bonducella extract showed good antifungal activity further supporting the potential medicinal application of this plant.The current study concluded the Caesalpinia bonducella extract significant effect of antioxidant and antifungal property