Plasma apolipoproteins and memory function in alcohol use disorder: Findings in male C57BL/6J mice and men suggest a role for <scp>APOAI</scp>
Both CIE-2BC mice and AUD patients exhibited elevated plasma levels of APOAI during early abstinence. APOAI correlated with poorer memory performance in both species, suggesting a potential role for this apolipoprotein in the context of alcohol-induced cognitive impairment.
Authors
- Candice Contet (ORCID: https://orcid.org/0000-0002-4459-9540)
- Berta Escudero (ORCID: https://orcid.org/0000-0001-8968-766X)
- Kiera Fleck (ORCID: https://orcid.org/0000-0002-9572-8314)
- Laura Orío (ORCID: https://orcid.org/0000-0002-9614-4062)
- Max Kreifeldt (ORCID: https://orcid.org/0000-0003-2136-6119)
- Catherine Lopez (ORCID: https://orcid.org/0009-0005-4693-7012)
Institutions
- Universidad Complutense de Madrid (ES)
- Scripps Research Institute (US)
- Research Institute Hospital 12 de Octubre (ES)
- Hospital Universitario 12 De Octubre (ES)
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
Publication Details
- Journal
- Alcohol Clinical and Experimental Research
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1111/acer.70149
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- National Institutes of Health
- Agencia Estatal de Investigación