A Retrospective Audit of Statin Prescription Practices in Diabetic Patients With Cardiovascular Risk

Background Diabetic patients are at increased risk of cardiovascular disease (CVD), and clinical guidelines recommend statin therapy for most individuals with diabetes aged ≥40 years or those with established atherosclerotic CVD (ASCVD). Objective The main objective of this audit was to evaluate the adherence to guideline-based statin prescribing practices among diabetic patients with cardiovascular risk and to identify gaps in prescription intensity and eligibility. Materials and methods A retrospective clinical audit was conducted on 131 diabetic patients at a tertiary care center. Data were collected retrospectively through a structured audit tool using patient medical records, including demographics (age, sex), duration of diabetes, comorbidities, lipid profile reports, cardiovascular history, and current statin prescription status (type, dose, and intensity). Results Out of 131 diabetic patients, 109 (83.2%) were eligible for statin therapy. Among them, 84 (77.1%) received any statin, while 25 (22.9%) remained untreated despite eligibility. High-intensity statins were prescribed in only 28 (33.3%) cases. Among patients with ASCVD (n = 34), 85.3% were on statins, but only 55.9% received high-intensity therapy. In patients without ASCVD but with risk factors (n = 75), 73.3% received statins, mostly moderate-intensity. Statin use was significantly higher in males (83.8%) than in females (69.2%) (p = 0.041), and patients aged ≥50 were more likely to receive statins (p = 0.018). Conclusions This audit reveals underutilization and suboptimal dosing of statins in diabetic patients, especially among women and younger individuals. Strengthening clinical adherence through guideline dissemination, audit-feedback cycles, and electronic decision support systems may improve cardiovascular outcomes in this high-risk group.

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Journal
Cureus
Published
2025-08-15
DOI
https://doi.org/10.7759/cureus.90152
Citations
1
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
2.01
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article

A Retrospective Audit of Statin Prescription Practices in Diabetic Patients With Cardiovascular Risk

Ali Husnain, Sabih Nofal, Muhammad Farhan Khaliq, Muhammad Zarrar Arif Butt et al.
1 citations
Cureus
Lipoproteins and Cardiovascular Health
2.01
article

A Retrospective Audit of Statin Prescription Practices in Diabetic Patients With Cardiovascular Risk

Ali Husnain, Sabih Nofal, Muhammad Farhan Khaliq, Muhammad Zarrar Arif Butt, Saadia Kanwal, Sharjeel Israr, Muhammad Hayat
article en
1 citations

Abstract

Background Diabetic patients are at increased risk of cardiovascular disease (CVD), and clinical guidelines recommend statin therapy for most individuals with diabetes aged ≥40 years or those with established atherosclerotic CVD (ASCVD). Objective The main objective of this audit was to evaluate the adherence to guideline-based statin prescribing practices among diabetic patients with cardiovascular risk and to identify gaps in prescription intensity and eligibility. Materials and methods A retrospective clinical audit was conducted on 131 diabetic patients at a tertiary care center. Data were collected retrospectively through a structured audit tool using patient medical records, including demographics (age, sex), duration of diabetes, comorbidities, lipid profile reports, cardiovascular history, and current statin prescription status (type, dose, and intensity). Results Out of 131 diabetic patients, 109 (83.2%) were eligible for statin therapy. Among them, 84 (77.1%) received any statin, while 25 (22.9%) remained untreated despite eligibility. High-intensity statins were prescribed in only 28 (33.3%) cases. Among patients with ASCVD (n = 34), 85.3% were on statins, but only 55.9% received high-intensity therapy. In patients without ASCVD but with risk factors (n = 75), 73.3% received statins, mostly moderate-intensity. Statin use was significantly higher in males (83.8%) than in females (69.2%) (p = 0.041), and patients aged ≥50 were more likely to receive statins (p = 0.018). Conclusions This audit reveals underutilization and suboptimal dosing of statins in diabetic patients, especially among women and younger individuals. Strengthening clinical adherence through guideline dissemination, audit-feedback cycles, and electronic decision support systems may improve cardiovascular outcomes in this high-risk group.

CureusVol. 17(8)
Shalamar Hospital (PK), Services Hospital (PK), University of Okara (PK), Memorial Hospital (US)
Good health and well-being
Openalex Percentile: Top 12%
Lipoproteins and Cardiovascular Health
2.01
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