An Integrated Microscope for High Throughput Imaging of Circulating Tumour Cells on a Chip
Circulating tumor cells (CTCs) are cells that shed from primary tumors into the bloodstream, leading to the formation of metastases. Their presence and numbers reflect the tumor burden, making them valuable biomarkers. Consequently, a simple blood draw can be used to non-invasively monitor tumor progression and treatment efficacy, a rapidly growing approach known as liquid biopsy [1]. However, the extreme rarity and heterogeneity of CTCs pose significant challenges for their identification, requiring methods that are often time-consuming, complex, and expensive.
Authors
- Serena Di Cosimo (ORCID: https://orcid.org/0000-0002-4666-8052)
- Giulia Bertolini (ORCID: https://orcid.org/0000-0002-8495-4594)
- Cinzia De Marco (ORCID: https://orcid.org/0000-0003-1153-270X)
- Martina Russo (ORCID: https://orcid.org/0000-0001-9886-9086)
- Petra Paiè (ORCID: https://orcid.org/0000-0002-6575-1986)
- Giacomo Corrielli (ORCID: https://orcid.org/0000-0002-1329-8972)
- Roberto Osellame (ORCID: https://orcid.org/0000-0002-4457-9902)
- Francesca Bragheri (ORCID: https://orcid.org/0000-0003-0172-0774)
- Nadia Brancati (ORCID: https://orcid.org/0000-0001-9061-1187)
- Andrea Ciceri
Institutions
- Institute for High Performance Computing and Networking (IT)
- Istituto di Fotonica e Nanotecnologie (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Politecnico di Milano (IT)
Publication Details
- Published
- 2025-06-23
- DOI
- https://doi.org/10.1109/cleo/europe-eqec65582.2025.11110604
- Primary Topic
- Nanofabrication and Lithography Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00