A Ready-to-use Compact Light Engine for Quantum Microscopy

Infrared (IR) sensing has a significant potential in applications ranging from cellular imaging to environmental sciences [1]. A primary challenge in the field has been the lack of efficient IR detectors. Quantum imaging with undetected light (QIUL) [2] is a new powerful imaging tool. QIUL relies on the nonlinear interferometry, using induced coherence [3], which allows the spectral separation of sensing and detection, facilitating imaging in hard-to-access spectral regions like ultraviolet or IR. These spectral regions contain relevant information for the identification of protein, lipid, and nucleic acid content [1], [4]. The core of our work involves the design, construction, and characterization of a quantum light engine tailored for scanning microscopy with undetected light, presenting a ready-to-use implementation of a ground-breaking approach to overcome the limitations of traditional IR sensing technologies while using low illumination regime.

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Published
2025-06-23
DOI
https://doi.org/10.1109/cleo/europe-eqec65582.2025.11109544
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
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article

A Ready-to-use Compact Light Engine for Quantum Microscopy

Markus Gräfe, Adrià Sansa Perna, Oliver de Vries, Vasile-Laurenţiu Dosan et al.
Advanced Fluorescence Microscopy Techniques
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A Ready-to-use Compact Light Engine for Quantum Microscopy

Markus Gräfe, Adrià Sansa Perna, Oliver de Vries, Vasile-Laurenţiu Dosan, Alek Lagarrigue, Dobryna Zalvidea, Valerio Flavio Gili, J. Torres
article en

Abstract

Infrared (IR) sensing has a significant potential in applications ranging from cellular imaging to environmental sciences [1]. A primary challenge in the field has been the lack of efficient IR detectors. Quantum imaging with undetected light (QIUL) [2] is a new powerful imaging tool. QIUL relies on the nonlinear interferometry, using induced coherence [3], which allows the spectral separation of sensing and detection, facilitating imaging in hard-to-access spectral regions like ultraviolet or IR. These spectral regions contain relevant information for the identification of protein, lipid, and nucleic acid content [1], [4]. The core of our work involves the design, construction, and characterization of a quantum light engine tailored for scanning microscopy with undetected light, presenting a ready-to-use implementation of a ground-breaking approach to overcome the limitations of traditional IR sensing technologies while using low illumination regime.

Fraunhofer Institute for Applied Optics and Precision Engineering (DE), Isotopen Technologien München (Germany) (DE), Friedrich Schiller University Jena (DE)
Affordable and clean energy
Openalex Percentile: Top 84%
Advanced Fluorescence Microscopy Techniques
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