Gastrointestinal Stromal Tumor of the Pancreas With Hepatic Metastasis Presenting as Obstructive Jaundice

Pancreatic gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that present significant diagnostic and treatment challenges due to their unusual location and vague symptoms. This report details an unusual case involving a male in the seventh decade of life who experienced obstructive jaundice resulting from a pancreatic GIST situated in the pancreaticoduodenal groove. Diagnosis was confirmed through imaging, histopathological analysis, and immunohistochemical studies. The patient received treatment with imatinib, which led to notable clinical improvement and considerable tumor reduction.

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Publication Details

Journal
Cureus
Published
2025-08-17
DOI
https://doi.org/10.7759/cureus.90277
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Gastrointestinal Stromal Tumor of the Pancreas With Hepatic Metastasis Presenting as Obstructive Jaundice

Fahad Saud Alanazi, Shakir Bakkari, Abdulaziz Alnasser, Khaled S. Alqahtani
Cureus
Gastrointestinal Tumor Research and Treatment
article

Gastrointestinal Stromal Tumor of the Pancreas With Hepatic Metastasis Presenting as Obstructive Jaundice

Fahad Saud Alanazi, Shakir Bakkari, Abdulaziz Alnasser, Khaled S. Alqahtani
article en

Abstract

Pancreatic gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that present significant diagnostic and treatment challenges due to their unusual location and vague symptoms. This report details an unusual case involving a male in the seventh decade of life who experienced obstructive jaundice resulting from a pancreatic GIST situated in the pancreaticoduodenal groove. Diagnosis was confirmed through imaging, histopathological analysis, and immunohistochemical studies. The patient received treatment with imatinib, which led to notable clinical improvement and considerable tumor reduction.

CureusVol. 17(8)
King Saud Medical City (SA)
Openalex Percentile: Top 67%
Gastrointestinal Tumor Research and Treatment
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