Metabolism of Lactobacillus and Gardnerella vaginalis in vaginal defined media
VDM more accurately models the metabolic activity and environmental effects of vaginal Lactobacillus species than BHI, particularly in terms of acidification and lactate production. Although G. vaginalis growth is limited in VDM, its characteristic metabolic pathways remain evident. These findings underscore the value of VDM in modelling key metabolic features of the vaginal microbiota, especially under conditions where Lactobacillus dominate or Gardnerella is prevalent.
Authors
- Rachel Marie Tribe (ORCID: https://orcid.org/0000-0003-3675-9978)
- A. James Mason (ORCID: https://orcid.org/0000-0003-0411-602X)
- Charlotte K. Hind (ORCID: https://orcid.org/0000-0002-3763-3106)
- J. Mark Sutton (ORCID: https://orcid.org/0000-0002-2288-0446)
- Victoria Horrocks (ORCID: https://orcid.org/0000-0003-4662-4321)
Institutions
- Defence Science and Technology Laboratory (GB)
- King's College London (GB)
Publication Details
- Journal
- Anaerobe
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1016/j.anaerobe.2025.102991
- Citations
- 1
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.18