Medical cannabis authorization and opioid milligram equivalents over time in patients with chronic pain: a retrospective analysis
In this longitudinal study of electronic health record data, MCA was not associated with a statistically significant decrease in OME over time. However, patients with long-term opioid use diagnostic code demonstrated a significantly higher endpoint OME. Future prospective research is needed to establish whether there are opioid-sparing effects of cannabis in humans.
Authors
- Timothy Furnish (ORCID: https://orcid.org/0000-0002-4615-3366)
- Carrie Cuttler (ORCID: https://orcid.org/0000-0002-5890-2985)
- Imanuel Lerman (ORCID: https://orcid.org/0000-0002-6564-7222)
- Nicholas C. Glodosky (ORCID: https://orcid.org/0000-0001-6098-3465)
- Michelle Sexton (ORCID: https://orcid.org/0000-0002-0443-8355)
- Greg Polston
- Nathaniel M. Schuster (ORCID: https://orcid.org/0000-0002-4970-6296)
- Michael J. Cleveland (ORCID: https://orcid.org/0000-0002-7649-1323)
- Euyhyun Lee
- Mark S. Wallace
Institutions
- University of California San Diego (US)
- Family Health Centers of San Diego (US)
- Washington State University (US)
Publication Details
- Journal
- Pain Medicine
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1093/pm/pnaf113
- Citations
- 1
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Georgia Clinical and Translational Science Alliance
- University of Oxford
- National Institutes of Health
- University of California, San Diego
- National Institute of Neurological Disorders and Stroke
- National Center for Complementary and Integrative Health