The Effects of Antipsychotic Dose Reduction on Movement Disorders and Cardiometabolic Indices in Patients Remitted from a First Episode of Psychosis
AP-dose reduction modestly benefits AP-related Parkinsonism, weight gain, cholesterol levels and potentially tardive dyskinesia in patients after FEP over time. These benefits should be carefully weighed against the risks of relapse and suicide.
Authors
- Selene Veerman
- Truus van den Brink
- Anton B. P. Staring (ORCID: https://orcid.org/0000-0002-4421-3265)
- Yinzhao Liu (ORCID: https://orcid.org/0000-0002-4156-4852)
- Gunnar Faber
- Marieke Begemann (ORCID: https://orcid.org/0000-0001-6448-2799)
- Martin D. de Jonge
- Ellen Graveland
- Matej Djordjevic
- Machteld Marcelis (ORCID: https://orcid.org/0000-0003-0045-9244)
- Thérèse van Amelsvoort (ORCID: https://orcid.org/0000-0003-1135-5133)
- Jim van Os (ORCID: https://orcid.org/0000-0002-7245-1586)
- Martijn Kikkert
- Benjamin I. Perry (ORCID: https://orcid.org/0000-0002-1533-026X)
- Erna van’t Hag
- Nynke Boonstra (ORCID: https://orcid.org/0000-0003-3592-1953)
- Albert Batalla (ORCID: https://orcid.org/0000-0002-5010-5121)
- Iris E. Sommer (ORCID: https://orcid.org/0000-0001-5597-3262)
- Simone Kamphuis
- Sybren Wiersma
- Shiral S. Gangadin (ORCID: https://orcid.org/0000-0002-0084-8226)
- Joran Lokkerbol (ORCID: https://orcid.org/0000-0001-9949-5442)
- Bodyl A. Brand (ORCID: https://orcid.org/0000-0003-2383-0851)
- Sanne Koops
- Natalie D. Veen
- Joelle Hoornaar
- Toon Anton Willem Scheurink (ORCID: https://orcid.org/0000-0002-2944-2924)
- Koen P. Grootens (ORCID: https://orcid.org/0000-0001-7458-107X)
- P. Roberto Bakker (ORCID: https://orcid.org/0000-0002-9964-9939)
- Steven Berendsen (ORCID: https://orcid.org/0000-0003-4080-5009)
- Karin Huizer (ORCID: https://orcid.org/0000-0002-0932-8139)
- Filip Smit (ORCID: https://orcid.org/0000-0001-9479-3600)
- Maarten Bak (ORCID: https://orcid.org/0000-0003-1822-5542)
- J. Joris Hage (ORCID: https://orcid.org/0000-0003-1790-0702)
- Jörg Kurkamp
- Alban Voppel
- Priscilla P. Oomen (ORCID: https://orcid.org/0000-0001-8430-0905)
- Henderikus Knegtering
- Ben F. M. Wijnen (ORCID: https://orcid.org/0000-0001-7993-1905)
- Franciska de Beer
- Bram‐Sieben Rosema
- Wim Veling (ORCID: https://orcid.org/0000-0002-1364-9779)
- Sinan Gülöksüz (ORCID: https://orcid.org/0000-0002-6626-1874)
- Iris M. H. Hamers (ORCID: https://orcid.org/0009-0007-0296-3969)
- Lieuwe de Haan
- Nico van Beveren
- Nico J.M. van Beveren
- Gerdina Hendrika Maria Pijnenborg
- Jort Noorman
- Ruben Curfs
- Inge Hobus
Institutions
- University Medical Center Groningen (NL)
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- Maastricht University (NL)
- Parnassia Groep (NL)
- Arkin (NL)
- Reinier van Arkel (NL)
- University of Birmingham (GB)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-06-28
- DOI
- https://doi.org/10.1093/schbul/sbaf116
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- ZonMw