Improvement of schizoaffective disorder with endoxifen treatment: a case report

Schizoaffective disorder shares symptomatology and pathophysiology with schizophrenia and bipolar disorder. Studies related to treatment option and their efficacy in schizoaffective disorder are limited; thus, no current consensus treatment guidelines exist. Patients with schizoaffective disorders are treated mainly with combination of antipsychotics and mood stabilizers or antidepressants. Here, the author presents a case of schizoaffective disorders that was successfully treated with endoxifen, which had efficacy issues with amisulpride, quetiapine, and risoperidone and safety issues with clozapine.

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Publication Details

Journal
International Journal of Basic & Clinical Pharmacology
Published
2025-08-22
DOI
https://doi.org/10.18203/2319-2003.ijbcp20252589
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Improvement of schizoaffective disorder with endoxifen treatment: a case report

Shvetha Chilukuri
International Journal of Basic & Clinical Pharmacology
Bipolar Disorder and Treatment
article

Improvement of schizoaffective disorder with endoxifen treatment: a case report

Shvetha Chilukuri
article en

Abstract

Schizoaffective disorder shares symptomatology and pathophysiology with schizophrenia and bipolar disorder. Studies related to treatment option and their efficacy in schizoaffective disorder are limited; thus, no current consensus treatment guidelines exist. Patients with schizoaffective disorders are treated mainly with combination of antipsychotics and mood stabilizers or antidepressants. Here, the author presents a case of schizoaffective disorders that was successfully treated with endoxifen, which had efficacy issues with amisulpride, quetiapine, and risoperidone and safety issues with clozapine.

International Journal of Basic & Clinical PharmacologyVol. 14(5)
Asha Hospital (IN)
Openalex Percentile: Top 74%
Bipolar Disorder and Treatment
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