Numerical modeling of non-Fourier bioheat transfer in multilayer biological tissue using BEM to simulate dynamic thermography in skin tumor diagnostics

This paper presents a novel approach for modeling non-Fourier dual-phase-lag bioheat transfer in multilayer biological tissue, aimed at simulating dynamic thermography for the early detection of skin tumors at Clark II and IV stages. The proposed algorithm, based on the boundary element method, enables the assignment of distinct thermophysical properties and non-Fourier relaxation time parameters to each tissue layer, thereby enhancing the realism of bioheat transfer modeling. Results show that accounting for non-Fourier effects significantly impacts the transient thermal contrast between tumor and healthy skin, particularly in Clark IV tumors and at higher relaxation times. These findings support the development of more accurate and physiologically realistic models of heat transfer in complex biological structures, and advance the application of dynamic thermography in early skin tumor detection and the diagnosis of other dermatological conditions.