Gliosarcoma: A Reported Case

Gliosarcoma is a rare aggressive variant of glioblastoma, classified as WHO grade IV a rare and aggressive variant of glioblastoma, affecting men between the ages of 50 and 60. It is characterized by a biphasic histological pattern combining glial and mesenchymal components. The pathogenesis remains debated. Prognosis remains poor, with median survival ranging from 8 to 17 months. Gliosarcoma remains a diagnostic and therapeutic challenge. Despite histological similarities with GBM, its distinct clinical behavior and metastatic potential warrant further investigation to improve management strategies and patient outcomes. This case study aimed to demonstrate the anatomopathology of gliosarcoma, and its aggressiveness.

Authors

Publication Details

Journal
Scholars Journal of Medical Case Reports
Published
2025-08-20
DOI
https://doi.org/10.36347/sjmcr.2025.v13i08.036
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Gliosarcoma: A Reported Case

M. Darfaoui, S. Laatitioui, S. Barkiche, M. Saadoune et al.
Scholars Journal of Medical Case Reports
Glioma Diagnosis and Treatment
article

Gliosarcoma: A Reported Case

M. Darfaoui, S. Laatitioui, S. Barkiche, M. Saadoune, Mouna Khouchani, N. Oumghar, Abdelhamid El Omrani, EL Batoul EL BYOUZI, Nouhaila BOURRAS
article en

Abstract

Gliosarcoma is a rare aggressive variant of glioblastoma, classified as WHO grade IV a rare and aggressive variant of glioblastoma, affecting men between the ages of 50 and 60. It is characterized by a biphasic histological pattern combining glial and mesenchymal components. The pathogenesis remains debated. Prognosis remains poor, with median survival ranging from 8 to 17 months. Gliosarcoma remains a diagnostic and therapeutic challenge. Despite histological similarities with GBM, its distinct clinical behavior and metastatic potential warrant further investigation to improve management strategies and patient outcomes. This case study aimed to demonstrate the anatomopathology of gliosarcoma, and its aggressiveness.

Scholars Journal of Medical Case ReportsVol. 13(08)
No poverty
Openalex Percentile: Top 71%
Glioma Diagnosis and Treatment
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