Body Composition and Kidney Outcomes: A Cohort Study of Rapid Kidney Function Decline and a Mendelian Randomization Analysis of CKD Incidence
Lower appendicular lean mass index and sarcopenic obesity were associated with RKFD. Higher leg and whole-body fat percentages and lower appendicular muscle mass significantly contribute to CKD risk, highlighting the importance of body composition in kidney health.
Authors
- Kaixin Li (ORCID: https://orcid.org/0000-0002-7184-6877)
- Yao Liu (ORCID: https://orcid.org/0000-0002-2775-1643)
- Zhibin Ye (ORCID: https://orcid.org/0000-0002-4057-1663)
- Jiaxi Zhao
Institutions
- Fudan University (CN)
- West China Medical Center of Sichuan University (CN)
- Huadong Hospital (CN)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1016/j.xkme.2025.101087
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Science and Technology of the People's Republic of China